Purified Human Interleukin-2
Purified, native human Interleukin-2 (IL-2) Human T-cell growth factor.
For research use only.
APPLICATION FOR USE
- Monocyte/Macrophage Culture
- Longterm Culture of Human T-lymphocytes
- IL-2 Stimulated T-Cell Proliferation Assay
QUALITY CONTROL TESTING INCLUDES
- Biological Activity
SHIPPING AND STORAGE:
This product is shipped frozen on dry ice. Store at -70°C upon receipt. Avoid multiple freeze-thaw cycles as product degradation may result.
This biological preparation should be handled in accordance with biosafety guidelines defined in the BMBL, NIH-CDC HHS Publication No. (CDC) 21-1112.
SAFE HANDLING RECOMMENDATIONS:
This product was tested and found negative for HBsAg, anti-HIV-1/2, anti-HCV, and HIV antigen. No test guarantees a product to be completely non-infectious. Therefore, all human blood derived material should be considered as potentially infectious and handled in accordance with biosafety guidelines defined in the BMBL, NIH-CDC HHS Publication No. (CDC) 21-1112.
Song, H., Giorgi, E., Ganusov, V., Cai, F., Athreya, G., Yoon, H., Carja, O., Hora, B., Hraber, P., and Romero-Severson, E. et al. (2018). Tracking HIV-1 recombination to resolve its contribution to HIV-1 evolution in natural infection. Nature Communications 9:1928. https://doi.org/10.1038/s41467-018-04217-5
Matsuda, K., Riddick, N., Lee, C., Puryear, S., Wu, F., Lafont, B., Whitted, S., and Hirsch, V. (2017). A SIV molecular clone that targets the CNS and induces neuroAIDS in rhesus macaques. PLOS Pathogens 13, e1006538. https://doi.org/10.1371/journal.ppat.1006538
Prasad, A., Kulkarni, R., Jiang, S., and Groopman, J. (2017). Cocaine Enhances DC to T-cell HIV-1 Transmission by Activating DC-SIGN/LARG/LSP1 Complex and Facilitating Infectious Synapse Formation. Scientific Reports 7, 40648. https://doi.org/10.1038/srep40648
Song, H., Hora, B., Giorgi, E., Kumar, A., Cai, F., Bhattacharya, T., Perelson, A., and Gao, F. (2016). Transmission of Multiple HIV-1 Subtype C Transmitted/founder Viruses into the Same Recipients Was not Determined by Modest Phenotypic Differences. Scientific Reports 6, 38130. https://doi.org/10.1038/srep38130
Nagaraja, T., Anand, A., Zhao, H., and Ganju, R. (2012). The Adaptor Protein SLP-76 Regulates HIV-1 Release and Cell-to-Cell Transmission in T Cells. The Journal Of Immunology 188, 2769-2777. https://doi.org/10.4049/jimmunol.1102106
Devadas, K., and Dhawan, S. (2006). Hemin Activation Ameliorates HIV-1 Infection via Heme Oxygenase-1 Induction. The Journal Of Immunology 176, 4252-4257. https://doi.org/10.4049/jimmunol.176.7.4252
Potula, R., Poluektova, L., Knipe, B., Chrastil, J., Heilman, D., Dou, H., Takikawa, O., Munn, D., Gendelman, H., Persidsky, Y. (2005). Inhibition of indoleamine 2,3-dioxygenase (IDO) enhances elimination of virus-infected macrophages in an animal model of HIV-1 encephalitis. Blood 106, 2382-2390. https://doi.org/10.1182/blood-2005-04-1403
Chernock, R., Cherla, R., and Ganju, R. (2001). SHP2 and cbl participate in alpha-chemokine receptor CXCR4-mediated signaling pathways. Blood 97, 608-615. https://doi.org/10.1182/blood.v97.3.608
Wyatt, L., and Frenkel, N. (1992). Human herpesvirus 7 is a constitutive inhabitant of adult human saliva. Journal of Virology 66, 3206-3209.
- New Product
- Available as Custom Product-Discontinued
- Limited Quantities Remaining-Discontinued
- Call For Availability
- Biohazard Category A
- Biohazard Category B