HIV-2 (NIH-Z Strain) Purified Virus

Catalog #: 10-127-000

Size: 1.0 mg

Biological Substance A

This material requires a signed and fully executed Advanced Biotechnologies Inc agreement with possible fees, prior to purchase. To begin this process, please complete the Intended Use form and return it to agreements@abionline.com.

Intended Use Form

DETAILS RESOURCES RELATED PRODUCTS

Human Immunodeficiency Virus type 2 (NIH-Z Strain) propagated in HuT 78 cells and purified from culture supernatant and cells showing cytopathic effect.

≥ 5 x 10¹⁰ viral particles per mL of purified HIV-2

For research use only.

APPLICATION FOR USE

In vitro Infectivity Assay
Antiviral Studies
Spiking Studies
Virus Neutralization Assay
Virus Ultrastructural Studies
Nucleic Acid-Based Assay

QUALITY CONTROL TESTING INCLUDES

Sterility
TCID50
Protein Concentration
Virus Particle Count

SHIPPING AND STORAGE:

This product is shipped frozen on dry ice. Store at -70°C upon receipt. Avoid multiple freeze-thaw cycles as product degradation may result.

RECOMMENDATIONS:

Upon thawing, centrifuge the vial for a few seconds to remove residual droplets from the lid.

SAFE HANDLING RECOMMENDATIONS:

This preparation of HIV is a BIOHAZARDOUS material containing ACTIVE VIRUS and should be handled in accordance with biosafety guidelines defined in the BMBL, NIH-CDC HHS Publication No. (CDC) 21-1112.

DOCUMENTATION

Certificate of Analysis

Safety Data Sheet

300-10-127-000

REFERENCE ARTICLES

Palm, A., Lemey, P., Jansson, M., Månsson, F., Kvist, A., Szojka, Z., Biague, A., da Silva, Z., Rowland-Jones, S., and Norrgren, H. et al. (2019). Low Postseroconversion CD4+ T-cell Level Is Associated with Faster Disease Progression and Higher Viral Evolutionary Rate in HIV-2 Infection. mBio 10, e01245-18. https://doi.org/10.1128/mbio.01245-18

Trevino, A., Soriano, V., Poveda, E., Parra, P., Cabezas, T., Caballero, E., Roc, L., Rodriguez, C., Eiros, J., and Lopez, M. et al. (2014). HIV-2 viral tropism influences CD4+ T cell count regardless of viral load. Journal Of Antimicrobial Chemotherapy 69, 2191-2194. https://doi.org/10.1093/jac/dku119

Damond, F., Benard, A., Balotta, C., Boni, J., Cotten, M., Duque, V., Ferns, B., Garson, J., Gomes, P., and Goncalves, F. et al. (2011). An International Collaboration To Standardize HIV-2 Viral Load Assays: Results from the 2009 ACHI_EV_2E Quality Control Study. Journal Of Clinical Microbiology 49, 3491-3497. https://doi.org/10.1128/jcm.02389-10

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